The long background to my medical situation can be found here: http://23nlpeople.com/stomach-ache-but-only-at-night-nocturnal-abdominal-pain-and-what-i-did-about-it/(link opens in new tab/window)
For those just wanting details of where I went for the poop-transplant, the clinic details can be found by scrolling all the way down.
In a nutshell: I have suffered well over a decade of abdominal pains, but only at night. Undoubtedly caused by a chronic herpes infection affecting the nerve that governs the gut. I had it under control and was doing well. Then, in April 2020, I got COVID and it messed me up completely for 15 months (“long-COVID”) and despite recovering from COVID, my gut issues never settled down.
During this time, I discovered by chance that the anti-histamine and over-the-counter “sleeping medication” diphenhydramine (sold in the UK as Nytol and in the USA as Benadryl) eliminated the gut problem completely as long as I kept taking it. But long-term consumption of diphenhydramine is really bad and is connected to all sorts of neurological disorders.
In researching why this should eliminate my abdominal pain, I learned about mast cell activation.
Have you been told you have IBS – irritable bowel syndrome, either in the IBS-C (constipation) or IBS-D (the messier version)?
Then there are three words you want to start googling in a frenzy. MAST CELL ACTIVATION
A real quick summary of mast cells for you:
- you got them everywhere in the body.
- they are the cells that contain all that lovely histamine that will make you itch like hell when triggered by a triggering thing.
- anti-histamines inhibit these cells from releasing their histamine.
- you got a shit-load of them in your intestines.
- many foods will trigger them – especially fermented foods, and food high in nitrites (sausages, burgers, fish that isn’t fresh – basically anything that comes out of a tin or is preserved/processed in some way).
- this in turn causes neurogenic inflammation, visceral hypersensitivity, and impaired peristalsis.
I’ve lost count of how many healthcare professionals I’ve seen and literally no one ever mentioned this. I was just told to destress and take anti-depressants, go away, and to stop being annoying by being so persistently symptomatic.
Let me translate that line 6 for you: Histamine reactions in the gut cause nerve swelling, sensitivity, and lack of muscular function in the intestines. AKA: painful bloating and painful constipation.
The relationship between mucosal inflammatory cells, specific symptoms, and psychological functioning in youth with irritable bowel syndrome
Meenal Singh, Vivekanand Singh, Jennifer V. Schurman, Jennifer M. Colombo & Craig A. Friesen.
…Mast cells have been highly implicated in IBS pathogenesis in both IBS-C and IBS-D9,10. IBS has been associated with an increase in the density of degranulating mast cells, while the density of mast cells in close proximity to enteric nerves correlates with abdominal pain severity…
So, I began googling and googling. I was already aware of poop transplants and the role of the gut microbiota. Do this later, type the following words into Google and start studying: mast cell IBS fecal microbiota transplantation
Luckily, they don’t actually transplant the poop, but rather it’s just the cultures taken from the poop. So it’s all proper medical and everything.
There are several delivery methods – basically, you either swallow capsules containing the “ingredients”, or you get a small hosepipe up the butt and it is squirted in. Typically the poop cultures are taken from 10 different healthy and fully screened donors (the screening is extensive, lengthy, and very thorough), you get 1 donor a day – 1-day prep, 5 days poop-implants, 2-day break, 5 days poop implants, finish.
During this time, a number of medications are also given, mostly a probiotic preparation and 3 different pre-biotic preparations.
So, anyway, that’s the background. Here’s the video diary:
Arrival in Slovakia
Bowel prep the day before the first FMT implantation
First Implantation Completed
Second Implantation Completed
What’s that Smell???? The third implantation completed
Day 4: Fecal Microbiota Implantation – more Q&A, and no, I won’t give you my room number.
Infection Response – Not too well after day 5, faecal microbiota transplantation
Fecal Microbiota Implantation (Day 6) – Huge Improvement and Problems with “The FMT Community.”
Days 7 and 8. Discombobulation and mast cell activation (Fecal Microbiota Implantation – aka “poop transplant”)
Implant 9 completed. Doing GREAT! (fecal microbiota transplantation)
All poop implants finished! I can go home. (My fecal microbiota implant adventure ends)
Join My Youtube Membership Program: https://www.youtube.com/channel/UCc-eF8jMdKSWDa2puamJk1g/join
Top Tips for your poop transplant at IPPM.
- Choose accommodation that is close to the clinic. The IPPM clinic (details below) where I am staying has on-site accommodation. WARNING: the breakfast served here (6 euros a day) is awful, don’t bother. They don’t serve it at weekends.
- The reason for choosing somewhere really close is that you might not want to do too much walking after each implant, lest you poop yourself.
- If staying on-site, there is a Lidl opposite, and several restaurants nearby. Bring some crockery and cutlery with you. The rooms have a mini-fridge and a kettle. The WiFi here is excellent.
- The town is an affluent industrial town. The soundproofing in the hotel isn’t great, so bring earplugs. Many contractors come and go during the week. I have found everyone here to be super-friendly, cheerful, polite, and helpful. Finding someone who speaks English hasn’t been a problem.
- The town centre is about 20 minutes walk away, and Big Tescos is about 30 minutes walk. Everything is really easy to find owing to the layout of the town, and there is a slightly longer and more pleasant walk along the river (use the sports stadium as your navigation point).
- There’s not a great deal to do here unless you like pubs and winter sports. Bring recreation with you.
- Bring some laundry detergent with you. You’ll be able to dry your ‘smalls’ in the bathroom on the heated towel rails, which saves you from having to buy a jumbo box from Lidl.
- The big Tesco (open 6 am-8 pm every day) has an excellent pharmacy with English-speaking staff. You’ll find it at the far end at the front of the store as you go inside.
- ENGLISH PEOPLE: Bring your own tea bags with you and your own favourite mug. Trust me on this. This is a sausage and coffee nation.
- Bring a toilet roll with you. On your first day, which is bowel prep day, you will be grateful for something soft and abundant as the sins of your entire miserable life are purged from your body.
- As you will be wanting to retain the implant for as long as possible, be aware that after your implant you won’t be going out and may well need to lie down. If your implants are in the morning, you’ll be able to go out later in the day. If your implants are in the afternoon, do your shopping, etc., in the morning beforehand.
- Take a book with you, as you need to lie flat/on your side for a while afterwards.
- Be sure to have a good poop BEFORE you get your implant. This is important for obvious reasons.
- Have a good shower before you go for implants and make sure your ringer is squeaky clean. It’s the polite thing to do.
The IPPM Clinic – The Institute of Predictive and Personalized Medicine
Odbojárov 300/4, 955 01, Tovarníky (Topoľčany), Slovakia.
Tel. +421 911 212 838
Facebook page: https://www.facebook.com/ippm.sk/
The clinic is about a 1-hour drive from Bratislava airport, and 1.5 hours from Vienna.
The comments section is open below, do please share your experiences there.
- I cannot advise you if this treatment will work for you, please don’t ask me.
- I have no interest or ability to help you plan your travel etc. Please don’t ask me.